Anti-PU.1 (SPI-1) (B-Cell Marker) Monoclonal Antibody(Clone: PU1/2146)
Product Sizes
20 µg
£397.00
36-3186-20UG
100 µg
£716.00
36-3186-100UG
About this Product
- SKU:
- 36-3186
- Additional Names:
- Transcription Factor spi1; 31kDa Transforming Protein; Hematopoietic Transcription Factor PU.1; SFPI1; SPI1; SPIA; Spleen focus forming virus (SFFV) proviral integration oncogene spi1
- translate.label.attr.clone:
- PU1/2146
- Clonality:
- Monoclonal
- Extra Details:
- PU.1 is a member of the ETS family of transcription factors and is important for normal B-cell development. It is expressed in the myeloid lineage and in immature as well as mature B-lymphocytes; with the exception of plasma cells. PU.1 is expressed in germinal center B-cells and mantle B-cells. Various lymphomas are also positive for this marker. It is essential during early B-cell differentiation. The absence of PU.1 results in total block of B-cell development at the pre-pro stage. PU.1 plays a key role in normal myeloid differentiation; and regulates the expression of immunoglobulin and other genes that are important for B-cell development.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa 16-170) of human PU.1 protein (Exact sequence is proprietary)
- Isotype:
- Mouse IgG2b; kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
