Anti-SOX2 (Embryonic Stem Cell Marker) Monoclonal Antibody(Clone: rSOX2/1791)
Product Sizes
20 µg
£397.00
36-3168-20UG
100 µg
£716.00
36-3168-100UG
About this Product
- SKU:
- 36-3168
- Additional Names:
- ANOP3; Delta EF2a; MCOPS3 (Microphthalmia Syndromic type 3); SOX-2; SRY (sex determining region Y) box 2; SRY related HMG box 2; Transcription factor SOX-2; ysb
- translate.label.attr.clone:
- rSOX2/1791
- Clonality:
- Monoclonal
- Extra Details:
- SOX2 is required for stem cell maintenance in the central nervous system; and it also regulates gene expression in the stomach. SOX2 is necessary for regulating multiple transcription factors that affect Oct 3/4 expression. An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct 3/4 expression. Reportedly; SOX2 is associated with aggressive phenotypes of breast; head and neck; gastric; colorectal; bladder; and small cell lung cancers. However; SOX2 is expressed in a high percentage of lung squamous cell carcinomas and has been shown to be an independent favorable prognostic marker.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (within aa176-305) of human SOX2 protein (exact sequence is proprietary)
- Isotype:
- Mouse IgG1; kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
