Anti-gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) Monoclonal Antibody(Clone: PMEL/2038)
Product Sizes
20 µg
£397.00
36-3155-20UG
100 µg
£716.00
36-3155-100UG
About this Product
- SKU:
- 36-3155
- Additional Names:
- 95kDa melanocyte-specific secreted glycoprotein; M-beta; Melanocyte lineage specific antigen GP100; Melanocyte protein Pmel 17; Melanoma associated ME20 antigen; Melanosomal matrix protein17; Premelanosome protein (PMEL17); Secreted melanoma-associated ME20 antigen; SILV; Silver homolog
- translate.label.attr.clone:
- PMEL/2038
- Clonality:
- Monoclonal
- Extra Details:
- Cytotoxic T lymphocytes (CTL's) recognize melanoma-associated antigens; which belong to three main groups. These groups include tumor-associated testis-specific antigens; melanocyte differentiation antigens and mutated or aberrantly expressed antigens; which are routinely used as markers to identify melanomas based on their binding to specific monoclonal antibodies. gp100; also designated ME20-M; ME20-S and PMEL 17; is classified as a melanocyte differentiation antigen and is expressed at low levels in normal cell lines and tissues; but is upregulated in melanocytes. gp100 is a highly glycosylated protein. It is also the product of proteolytic cleavage; which results in a secreted protein.
- Host:
- Mouse
- Immunogen:
- A recombinant fragment (around aa 376-502) of human SILV protein (exact sequence is proprietary)
- Isotype:
- Mouse IgG1; kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
