Anti-SDHB (Succinate Dehydrogenase B) (Pheochromocytoma Marker) Monoclonal Antibody(Clone: SDHB/2382)
Product Sizes
20 µg
£397.00
36-3140-20UG
100 µg
£716.00
36-3140-100UG
About this Product
- SKU:
- 36-3140
- Additional Names:
- CWS2; DHSB; Iron-sulfur subunit of complex II; PGL4; SDH2; SDHB; SDHIP; Succinate dehydrogenase [ubiquinone] iron-sulfur subunit; mitochondrial; Succinate Dehydrogenase Complex Subunit B Iron Sulfur Protein
- translate.label.attr.clone:
- SDHB/2382
- Clonality:
- Monoclonal
- Extra Details:
- Succinate dehydrogenase (SDH) is Complex II in the mitochondria; vital for mitochondrial electron transport; as well as Krebs cycle function.Four subunits comprise the SDH protein complex: a flavochrome subunit (SDHA); an iron-sulfur protein (SDHB) and two membrane-bound subunits (SDHC and SDHD) anchored to the inner mitochondrial membrane. The SDH complex functions as a tumor suppressor. Loss of any subunit proteins lead to destabilization of the complex and tumor formation.Antibody to SDHB is helpful in the identification of phaeochromocytomas; paragangliomas and GIST.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa 165-273) of human SDHB protein (exact sequence is proprietary)
- Isotype:
- Mouse IgG2b; kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
