Anti-Bcl-6 (Follicular Lymphoma Marker) Monoclonal Antibody(Clone: BCL6/2497R)
Product Sizes
20 µg
£397.00
36-3112-20UG
100 µg
£716.00
36-3112-100UG
About this Product
- SKU:
- 36-3112
- Additional Names:
- B-cell lymphoma 5 protein; B-Cell Lymphoma 6 Protein; BCL5; BCL6; BCL6A; cys his2 zinc finger transcription factor; Lymphoma Associated Zinc Finger Gene On Chromosome 3 (LAZ3); Zinc finger and BTB domain-containing protein 27 (ZBTB27); Zinc Finger Protein 51 (ZNF51); zinc finger transcription factor
- translate.label.attr.clone:
- BCL6/2497R
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a protein of 95kDa; which is identified as Bcl-6. Antibody to bcl-6 is helpful in a number of diagnostic settings: (1) In the differential diagnosis of small B-cell lymphoma. Follicular lymphoma will show bcl-6 (and CD10) positivity whereas other small B-cell lymphomas are usually negative. (2) Bcl-6 is an important prognostic marker in diffuse large B-cell lymphomas (DLBCL); where CD10; bcl-6 and MUM1/IRF4 are used to identify germinal center and activated B-cell phenotypes. (3) Bcl-6 can be valuable in distinguishing classical Hodgkin lymphoma from nodular lymphocyte predominant Hodgkin lymphoma (NLPHL). The Reed-Sternberg cells of classical Hodgkin lymphoma are bcl-6 negative whereas the large ('LH') cells of NLPHL are bcl-6 positive. In contrast; anti-Bcl-6 rarely stains mantle-cell lymphoma and MALT lymphoma.
- Host:
- Rabbit
- Immunogen:
- Recombinant human bcl-6 protein fragment (aa256-389) (exact sequence is proprietary)
- Isotype:
- Rabbit IgG
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
