Anti-RET Proto-oncogene Monoclonal Antibody(Clone: RET/2663)
Product Sizes
20 µg
£397.00
36-3096-20UG
100 µg
£716.00
36-3096-100UG
About this Product
- SKU:
- 36-3096
- Additional Names:
- Cadherin family member 12 (CDHF12); Cadherin related family member 16 (CDHR16); ELKS; HSCR1; Hydroxyaryl protein kinase; MEN2A; MEN2B; MTC1; Multiple endocrine neoplasia and medullary thyroid carcinoma 1; Oncogene RET; Proto-oncogene c-Ret; Proto-oncogene tyrosine-protein kinase receptor ret; PTC; R
- translate.label.attr.clone:
- RET/2663
- Clonality:
- Monoclonal
- Extra Details:
- The Ret proto-oncogene is structurally related to the growing family of tyrosine kinase transmembrane receptors and is involved in GDNF signaling. RET expression is reported in several regions of the central nervous system; in the developing cranial nerve ganglia and a subset of cells within dorsal root ganglia; in motor neurons in the spinal cord and hindbrain; in neuro-retina and the growing tips of the renal collecting ducts in developing kidney.Alterations in RETgene are associated with diseases including papillary thyroid carcinoma; multiple endocrine neoplasia (type 2A and 2B); familial medullary thyroid carcinoma; and a congenital developmental disorder known as Hirschsprung's disease.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa 702-848) of human RET protein (exact sequence is proprietary)
- Isotype:
- Mouse IgG2b; kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
