Anti-Cyclin D1 (G1-Cyclin & Mantle Cell Lymphoma Marker) Monoclonal Antibody(Clone: CCND1/3548)
Product Sizes
20 µg
£397.00
36-3089-20UG
100 µg
£716.00
36-3089-100UG
About this Product
- SKU:
- 36-3089
- Additional Names:
- B cell CLL/lymphoma 1; B cell leukemia 1; B-cell lymphoma 1 protein; BCL-1 oncogene; CCND1 protein; CCND1/FSTL3 fusion gene; CCND1/IGHG1 fusion gene CCND1/IGLC1 fusion gene; CCND1/PTH fusion gene; G1/S-specific cyclin-D1; Parathyroid adenomatosis 1; PRAD1 oncogene
- translate.label.attr.clone:
- CCND1/3548
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a protein of 36kDa; identified as cyclin D1. Cyclin D1; one of the key cell cycle regulators; is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. This antibody neutralizes the activity of cyclin D1 in vivo. About 60% of mantle cell lymphomas (MCL) contain a t(11; 14)(q13; q32) translocation resulting in over-expression of cyclin D1. This antibody is useful in identifying mantle cell lymphomas (cyclin D1 positive) from CLL/SLL and follicular lymphomas (cyclin D1 negative). Occasionally; hairy cell leukemia and plasma cell myeloma weakly express Cyclin D1.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment of human CCND1 (around aa 115-270) protein (exact sequence is proprietary)
- Isotype:
- Mouse IgG2b; kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
