Anti-Beta-2 Microglobulin (Renal Failure & Tumor Marker) Monoclonal Antibody(Clone: C21.48A1)
Product Sizes
20 µg
£397.00
36-3049-20UG
100 µg
£716.00
36-3049-100UG
About this Product
- SKU:
- 36-3049
- Additional Names:
- B2M; Beta 2 microglobin; Beta 2 microglobulin; Beta chain of MHC class I molecules; Beta-2-microglobulin form pI 5.3; Hdcma22p
- translate.label.attr.clone:
- C21.48A1
- Clonality:
- Monoclonal
- Extra Details:
- The antibody recognizes the hidden determinant of beta-2 microglobulin (i.e. binding to its determinant is available only when the chain is separated from the HLA heavy chain. Beta-2 microglobulin is a 12KDa protein with a pI of 5.6. Serum beta2 microglobulin levels are a reflection of cell turnover. Levels rise with fever; inflammation; and infection. Increased serum levels are also seen in B-cell malignancies and in renal failure and may indicate a worse prognosis for patients with early-stage Hodgkin's lymphoma. In urine; increased levels are seen in proximal renal tubular disease as well as renal transplant rejection. Beta2 microglobulin levels can rise either because its rate of synthesis has increased (e.g. in AIDS; malignant monoclonal plasma cell dyscrasia; solid tumours and autoimmune disease) or because of impaired renal filtration (e.g. due to renal insufficiency; graft rejection or nephrotoxicity induced by post-transplantation immunosuppressive therapy).
- Host:
- Mouse
- Immunogen:
- Soluble beta 2 microglobulin
- Isotype:
- Mouse IgG2b; kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
