Skip to content

Basket

You currently have no items in your basket.

Total (excl. vat) £0.00
View basket & checkout
Antibodies

Anti-Beta-2 Microglobulin (Renal Failure & Tumor Marker) Monoclonal Antibody(Clone: BBM.1)

Product Sizes
20 µg
£397.00
36-3048-20UG
100 µg
£716.00
36-3048-100UG
About this Product
SKU:
36-3048
Additional Names:
B2M; Beta 2 microglobin; Beta 2 microglobulin; Beta chain of MHC class I molecules; Beta-2-microglobulin form pI 5.3; Hdcma22p
translate.label.attr.clone:
BBM.1
Clonality:
Monoclonal
Extra Details:
Recognizes a protein of 12kDa; identified as microglobulin. Major histocompatibility complex (MHC) class 1 molecules bind to antigens for presentation on the surface of cells. The proteasome is responsible for producing these antigens from the components of foreign pathogens. MHC class 1 molecules consist of an alpha heavy chain that contains three subdomains (alpha1; alpha2; alpha3) and a non-covalent associating light chain; known as beta-2-Microglobulin. Beta-2-Microglobulin associates with the alpha3 subdomain of the alpha heavy chain and forms an immunoglobulin domain-like structure that mediates proper folding and expression of MHC class 1 molecules. The alpha1 and alpha2 domains of the alpha heavy chain form the peptide antigen-binding cleft. Mutations in the beta-2-Microglobulin gene can enhance the progression of malignant melanoma phenotypes.
Host:
Mouse
Immunogen:
MOLT-4 human T cell line
Isotype:
Mouse IgG2b; kappa
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
  • Manufacturer's Data Sheet:1.jpg
Fig. 2: Western Blot Analysis of human Raji cell lysate using Beta-2-Microglobulin Mouse Monoclonal Antibody (BBM.1)
Fig. 3: Immunofluorescent staining of HeLa cells. Beta-2-Microglobulin Mouse Monoclonal Antibody (BBM.1) followed by goat anti-Mouse IgG-CF488 (Green). The nuclear counterstain is Reddot (Red)
Fig. 3: Immunofluorescent staining of HeLa cells. Beta-2-Microglobulin Mouse Monoclonal Antibody (BBM.1) followed by goat anti-Mouse IgG-CF488 (Green). The nuclear counterstain is Reddot (Red)