Anti-ENAH / MENA (Actin Regulator) Monoclonal Antibody(Clone: ENAH/1988)
Product Sizes
20 µg
£397.00
36-3036-20UG
100 µg
£716.00
36-3036-100UG
About this Product
- SKU:
- 36-3036
- Additional Names:
- ENA; ENAH; MENA; NDPP1
- translate.label.attr.clone:
- ENAH/1988
- Clonality:
- Monoclonal
- Extra Details:
- The Wiskott-Aldrich syndrome (WAS) is characterized by thrombocytopenia; eczema; defects in cell-mediated and humoral immunity and a propensity for lymphoproliferative diseases. The syndrome is the result of a mutation in the gene encoding a proline-rich protein termed WASP. WASP is a downstream effector of Cdc42 and has been implicated in actin polymerization and cyto- skeletal organization. Distantly related proteins; VASP (vasodilator-stimulated phosphoprotein) and Mena (for mammalian enabled protein); are involved in the regulation of cytoskeletal dynamics. Both Mena and VASP accumulate at focal adhesions. Mena is highly expressed in the developing nervous system and may be involved in growth cone motility and axon guidance.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment of human MENA protein (around aa 485-589) (exact sequence is proprietary)
- Isotype:
- Mouse IgG2c; kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
