Anti-ATRX / RAD54 (Alpha Thalassemia Mental Retardation) Monoclonal Antibody(Clone: 23c)
Product Sizes
20 µg
£397.00
36-2979-20UG
100 µg
£716.00
36-2979-100UG
About this Product
- SKU:
- 36-2979
- Additional Names:
- Alpha thalassemia/mental retardation syndrome X linked homolog; ATP-dependent helicase ATRX; ATR2; ATRX; DNA-dependent ATPase and helicase; MRXHF1; RAD54; RAD54L; SFM1; SHS; Transcriptional regulator ATRX; X-linked helicase II; X-linked nuclear protein; XH2; XNP; Znf-HX
- translate.label.attr.clone:
- 23c
- Clonality:
- Monoclonal
- Extra Details:
- ATRX is a member of the Snf2 family of helicase/ATPases; which contribute to the remodeling of the nucelosome structure in an ATP-dependent manner; and facilitate the initiation of transcription and replication. Structurally; ATRX contains a PHD zinc finger motif. ATRX is regulated throµghout the cell cycle where it is differentially distributed within the nucleus. During interphase; ATRX predominately associates with the nuclear matrix; while during mitosis; ATRX localizes with condensed chromatin. At the onset of M phase; phosphorylation rapidly induces this redistribution of ATRX to the short arms of human acrocentric chromosomes; where it then specifically complexes with heterochromatin protein 1 thalassemia or ATRX syndrome
- Host:
- Mouse
- Immunogen:
- Recombinant human ATRX protein
- Isotype:
- Mouse IgG1; kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
