Anti-OCT-2 (POU2F2) (B-Cell Marker) Monoclonal Antibody(Clone: 86474)
Product Sizes
20 µg
£397.00
36-2975-20UG
100 µg
£716.00
36-2975-100UG
About this Product
- SKU:
- 36-2975
- Additional Names:
- Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2; Oct-2; Octamer-binding protein 2; Octamer-binding transcription factor 2; OTF-2; POU domain class 2 transcription factor 2; POU2F2
- translate.label.attr.clone:
- Oct2-2136
- Clonality:
- Monoclonal
- Extra Details:
- Oct-2 is a transcription factor of the POU homeo-domain family that binds to the Ig gene octamer sites; regulating B-cell-specific genes. Oct-2 expression can be used as a marker of B-cell lineage and differentiation. Germinal center B-cells; mantle B-cells; monocytoid B-cells; and plasma cells show high level expression of Oct-2. Additionally; mantle cell lymphoma; follicular lymphoma; marginal zone lymphoma; plasmacytoma; Burkitt lymphoma; diffuse large cell lymphoma; diffuse large B-cell lymphoma; Hodgkin lymphoma display increased expression of Oct-2. Several studies of Oct-2 expression have shown a low level expression in pre-B; T-cell; myelomonocytic; and epithelial cell lines; whereas all mature B-cell lines have high levels of expression. In spite of scanty evidence for Oct-2 expression in T cells; it is believed that this factor participates in transcriptional regulation during T-cell activation.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment of human OCT2 protein (around aa 112-297) (exact sequence is proprietary)
- Isotype:
- Mouse IgG1; kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
