Anti-Plakophilin-1 (PKP1) Monoclonal Antibody(Clone: 10B2)
Product Sizes
20 µg
£397.00
36-2945-20UG
100 µg
£716.00
36-2945-100UG
About this Product
- SKU:
- 36-2945
- Additional Names:
- B6P; Band 6 protein; PKP1; Plakophilin-1 (ectodermal dysplasia/skin fragility syndrome)
- translate.label.attr.clone:
- 10B2
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a protein of 75kDa; identified as Plakophilin-1. Its epitope maps between aa 1-27 human Plakophilin-1. Plakophilins 1; 2; 3 and 4 (PKP1-4) influence development and participate in linking cadherins to cytoskeletal intermediate filaments. Plakophilins 1-4 contain arm-repeat (armadillo) domains and localize to nuclei and cell desmosomes (cell-cell junctions found in suprabasal layers of stratifying epithelia that undergo mechanical stress). Plakophilin 2 is important for desmosome assembly and is an essential morphogenic factor and architectural component of the heart.
- Host:
- Mouse
- Immunogen:
- N-terminus of human Plakophilin-1 protein
- Isotype:
- Mouse IgG1; kappa
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
