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Antibodies

Anti-Prohibitin (Mitochondrial Marker) Monoclonal Antibody(Clone: PHB/3193)

Product Sizes
20 µg
£397.00
36-2933-20UG
100 µg
£716.00
36-2933-100UG
About this Product
SKU:
36-2933
Additional Names:
Epididymis luminal protein 215; Epididymis secretory sperm binding protein Li 54e; HEL 215; HEL S 54e; PHB; PHB1; Prohibitin
translate.label.attr.clone:
PHB/3193
Clonality:
Monoclonal
Extra Details:
Recognizes a protein of 30kDa which is identified as Prohibitin; an evolutionarily conserved protein with homologues found in yeast to man. It is located in the inner membrane of mitochondria. Althoµgh prohibitin mRNA and protein expression occurs throµghout the cell cycle; maximum levels are detected during the G1/S phase transition and minimum levels are seen in S phase and the G2/mitosis boundary. Prohibitin is located exclusively in the mitochondria with the highest concentration on the inner membrane. Prohibitin is an ideal mitochondrial marker. It shows antiproliferative activity and has been proposed to play a role in normal cell cycle regulation; replicative senescence; cellular immortalization; and tumor suppression.
Host:
Mouse
Immunogen:
Recombinant human PHB protein fragment (aa167-261) (exact sequence is proprietary)
Isotype:
Mouse IgG2b; kappa
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
  • Manufacturer's Data Sheet:1.jpg
Fig. 2: Formalin-fixed; paraffin-embedded human Liver stained with Prohibitin Mouse Monoclonal Antibody (PHB/3193).
Fig. 3: SDS-PAGE Analysis Purified Prohibitin Mouse Monoclonal Antibody (PHB/3193). Confirmation of Purity and Integrity of Antibody.
Fig. 4: Analysis of Protein Array containing more than 19;000 full-length human proteins using Monospecific Mouse Monoclonal Antibody to Prohibitin (PHB/3193). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals ge
Fig. 4: Analysis of Protein Array containing more than 19;000 full-length human proteins using Monospecific Mouse Monoclonal Antibody to Prohibitin (PHB/3193). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals ge