Anti-NOX4 / NADPH Oxidase 4 Monoclonal Antibody(Clone: NOX4/1245)
Product Sizes
20 µg
£397.00
36-2891-20UG
100 µg
£716.00
36-2891-100UG
About this Product
- SKU:
- 36-2891
- Additional Names:
- Kidney oxidase-1; Kidney superoxide-producing NADPH oxidase; KOX-1; NADPH oxidase 4; Nox4; Renal NAD(P)H-oxidase; RENOX
- translate.label.attr.clone:
- NOX4/1245
- Clonality:
- Monoclonal
- Extra Details:
- The superoxide-generating NADPH oxidase includes a membrane-bound flavocytochrome containing two subunits; gp91-phox and p22-phox; and the cytosolic proteins p47-phox and p67-phox. During activation of the NADPH oxidase; p47-phox and p67-phox migrate to the plasma membrane where they associate with the flavocytochrome; cytochrome b558; to form the active enzyme complex. The p22 and gp91-phox subunits also function as surface O2 sensors that initiate cellular signaling in response to hypoxic conditions. NOX4 is a renal gp91-phox homolog highly expressed at the site of erythropoietin production in the proximal convoluted tubule epithelial cells of the renal cortex. It is also expressed in fetal tissues; placenta; glioblastoma and vascular cells.
- Host:
- Mouse
- Immunogen:
- Recombinant human NOX4 protein
- Isotype:
- Mouse IgG2b; kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
