Anti-Langerin / CD207 (Marker of Langerhans Cells) Monoclonal Antibody(Clone: LGRN/1821)
Product Sizes
20 µg
£397.00
36-2888-20UG
100 µg
£716.00
36-2888-100UG
About this Product
- SKU:
- 36-2888
- Additional Names:
- C-type lectin domain family 4 member K; CD207; CLEC4K; Langerhans cell specific c type lectin; Langerin
- translate.label.attr.clone:
- LGRN/1821
- Clonality:
- Monoclonal
- Extra Details:
- Langerhans cells (LCs) are a subset of immature dendritic cells (DCs) that specifically localize in the epidermis and other mucosal epithelia. Epidermal LCs possess strong immuno-stimulatory capacity and play a central role in the initiation and regulation of immune responses. Langerin (CD207) is a Ca2+-dependent; C-type lectin domain containing; type II transmembrane protein that induces epidermal LCs to differentiate into Birbeck granules (BG). BGs are organelles with superimposing and zippering membranes that influence proper class I type antigen presentation to the circulating T cells. Human spleen; lymph node; thymus; liver; lung and heart express Langerin protein.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa74-213) of human Langerin protein (exact sequence is proprietary)
- Isotype:
- Mouse IgG2a; kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
