Anti-NME1 / nm23-H1 / NDPK-A (Suppressor of Metastasis) Monoclonal Antibody(Clone: CPTC-NME1-2)
Product Sizes
20 µg
£397.00
36-2863-20UG
100 µg
£716.00
36-2863-100UG
About this Product
- SKU:
- 36-2863
- Additional Names:
- AWD; GAAD; Granzyme A activated DNase; Metastasis inhibition factor NM23; NB; NBS; NDP kinase A; NM23 long variant; included; NM23H1B; NME/NM23 nucleoside diphosphate kinase 1; NME1-NME2 spliced read-throµgh transcript; included; Non-metastatic protein 23; homolog 1; Nucleoside diphosphate kinase A
- translate.label.attr.clone:
- CPTC-NME1-2
- Clonality:
- Monoclonal
- Extra Details:
- The nm23 gene; a potential suppressor of metastasis; was originally identified by differential hybridization between two murine melanoma sub-lines; one with a high and the second with a low metastatic capacity. Highly metastatic sub-lines exhibit much lower levels of nm23 than less metastatic cells. Based on sequence analysis; nm23 appears highly related to nucleotide diphosphate kinases (NDP-K). In humans; NDP kinase A and B are identical to two isotypes of human nm23 homologs; namely nm23-H1 and H2; respectively. nm23-H2 is identical in sequence to PuF; a transcription factor that binds to nuclease hypersensitive elements at positions 142 to 115 of the human C-Myc promotor.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human NME1 protein
- Isotype:
- Mouse IgG2a; kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
