Anti-n-Myc (Neuroblastoma Marker) Monoclonal Antibody(Clone: NMYC-1)
Product Sizes
20 µg
£397.00
36-2834-20UG
100 µg
£716.00
36-2834-100UG
About this Product
- SKU:
- 36-2834
- Additional Names:
- Class E basic helix-loop-helix protein 37 (bHLHe37); MODED; N-myc proto-oncogene protein; Neuroblastoma derived v myc avian myelocytomatosis viral related oncogene; ODED; pp65/67; v myc (avian) myelocytomatosis viral related oncogene neuroblastoma derived
- translate.label.attr.clone:
- NMYC-1
- Clonality:
- Monoclonal
- Extra Details:
- The v-Myc oncogene; initially identified in the MC29 avian retrovirus; causes myelocytomas; carcinomas; sarcomas and lymphomas; and belongs to a family of oncogenes conserved throµghout evolution. In humans; the family consists of five genes: c-Myc; N-Myc; R-Myc; L-Myc and B-Myc. Amplification of the N-Myc gene has been found in human neuroblastomas and cell lines. Its amplification correlates well with the stage of neuroblastoma disease. Immunological studies have shown that the human N-Myc gene encodes a nuclear phosphoprotein that exhibits relatively short (30 min) half life in vivo. The prototype member of the family; c-Myc p67; binds DNA in a sequence-specific manner subsequent to dimerization with a second basic region helix-loop-helix leucine zipper motif protein; designated Max.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human n-Myc protein.
- Isotype:
- Mouse IgG2a; kappa
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
