Anti-c-Myb Oncoprotein Monoclonal Antibody(Clone: MYB286)
Product Sizes
20 µg
£397.00
36-2830-20UG
100 µg
£716.00
36-2830-100UG
About this Product
- SKU:
- 36-2830
- Additional Names:
- c-myb_CDS; efg; ONCOGENE AMV; Oncogene MYB; Proto-oncogene c-Myb; Transcriptional activator Myb; v-myb avian myeloblastosis viral oncogene homolog
- translate.label.attr.clone:
- MYB286
- Clonality:
- Monoclonal
- Extra Details:
- The highly leukemogenic avian retrovirus E26 contains two oncogenes; v-Myb and v-Ets; which are expressed together as a fusion protein. The cellular homolog of v-Myb; designated c-Myb; encodes a transcription factor. Deletion or disruption of a negative regulatory domain mapping within the carboxy-terminal domain of c-Myb results in enhanced transactivating capacity and in parallel; leads to activation of its ability to transform hemopoietic cells. c-Myb is expressed preferentially; but not exclusively; in immature hemopoietic cells and its expression decreases as cells differentiate.
- Host:
- Mouse
- Immunogen:
- A synthetic peptide; corresponding to aa 119-135 (RRKVEQEGYPQESSKAG) of c-myb onco protein; coupled to KLH
- Isotype:
- Mouse IgG1; kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
