Anti-MUC3 (Mucin 3) Monoclonal Antibody(Clone: MUC3/2992R)
Product Sizes
20 µg
£397.00
36-2821-20UG
100 µg
£716.00
36-2821-100UG
About this Product
- SKU:
- 36-2821
- Additional Names:
- Intestinal mucin-3A; intestinal mucin-like; MUC3; MUC3A; MUC3B; mucin 3; intestinal; mucin 3A; cell surface associated; mucin 3A; intestinal; mucin 3B; cell surface associated
- translate.label.attr.clone:
- MUC3/2992R
- Clonality:
- Monoclonal
- Extra Details:
- It recognizes a protein of HMW; identified as mucin 3 glycoprotein (MUC3). Its epitope localizes between aa SITTTE. This MAb shows no cross-reaction with human milk fat globule membranes; MUC1; or MUC2. MUC3 is distributed in colon and rectum; and is also present to a lesser extent in breast; lung and salivary gland tissues. The Mucins are a family of highly glycosylated; secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs) encoded by 60 base pairs (Mucin 1); 69 base pairs (Mucin 2) and 51 base pairs (Mucin 3). The number of repeats is highly polymorphic and varies among different alleles. Mucin 1 proteins are expressed as type I membrane proteins in addition to secreted forms. Mucin 1 is aberrantly expressed in epithelial tumors including breast carcinomas. Mucin 2 coats the epithelia of the intestines and airways and is associated with colonic tumors. Mucin 3 is a major component of various mucus gels and is broadly expressed in normal and tumor cells.
- Host:
- Rabbit
- Immunogen:
- A synthetic peptide of 35 amino acids; SIB35 (C-HSTPSFTSSITTTETTSHSTPSFTSSITTTETTS); which contains two of the MUC3 tandem repeats; coupled to KLH.
- Isotype:
- Rabbit IgG
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
