Anti-MSH2 (DNA Mismatch Repair Marker) Monoclonal Antibody(Clone: MSH2/2622)
Product Sizes
20 µg
£397.00
36-2801-20UG
100 µg
£716.00
36-2801-100UG
About this Product
- SKU:
- 36-2801
- Additional Names:
- BAT26; COCA1; DNA mismatch repair protein Msh2; FCC1; hMSH2; HNPCC1; LCFS2; MSH2; MutS homolog 2; MutS homolog 2 colon cancer nonpolyposis type 1; MutS protein homolog 2
- translate.label.attr.clone:
- MSH2/2622
- Clonality:
- Monoclonal
- Extra Details:
- Mutations in DNA mismatch repair genes are associated with hereditary nonpolyposis colorectal cancer (HNPCC). Initially; inherited mutations in the MSH2 and MLH1 homologs of the bacterial DNA mismatch repair genes MutS and MutL were found at high frequency in HNPCC and were shown to be associated with microsatellite instability. The demonstration that 10 to 45% of pancreatic; gastric; breast; ovarian and small cell lung cancers also display microsatellite instability has been interpreted to sµggest that DNA mismatch repair is not restricted to HNPCC tumors but is a common feature in tumor initiation or progression.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa 327-427) of human MSH2 protein (exact sequence is proprietary)
- Isotype:
- Mouse IgG1; kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
