Anti-CD99 / MIC2 (Ewing's Sarcoma Marker) Monoclonal Antibody(Clone: 12E7 + MIC2/877)
Product Sizes
20 µg
£397.00
36-2767-20UG
100 µg
£716.00
36-2767-100UG
About this Product
- SKU:
- 36-2767
- Additional Names:
- 12E7; E2 antigen; MIC 2X; MIC 2Y; MIC2; Protein MIC2; Surface antigen MIC2; T-cell surface glycoprotein E2
- translate.label.attr.clone:
- 12E7 + MIC2/877
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a sialoglycoprotein of 27-32kDa; identified as CD99; or MIC2 gene product; or E2 antigen. MIC2 gene is located in the pseudo-autosomal region of the human X and Y chromosome. MIC2 gene encodes two distinct proteins; which are produced by alternative splicing of the CD99 gene transcript and are identified as bands of 30 and 32kDa (p30/32).Althoµgh its function is not fully understood; CD99 is implicated in various cellular processes including homotypic aggregation of T cells; upregulation of T cell receptor and MHS molecules; apoptosis of immature thymocytes and leukocyte diapedesis.CD99 is expressed on the cell membrane of some lymphocytes; cortical thymocytes; and granulosa cells of the ovary. Most pancreatic islet cells; Sertoli cells of the testis; and some endothelial cells express this antigen. Mature granulocytes express very little or no CD99. MIC2 is strongly expressed on Ewing's sarcoma cells and primitive peripheral neuroectodermal tumors.
- Host:
- Mouse
- Immunogen:
- Human acute lymphocytic leukemia T-cells (12E7); Recombinant human MIC2 protein (MIC2/877)
- Isotype:
- Mouse IgG1; kappa + Mouse IgG1; kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
