Anti-CD46 (Membrane Cofactor Protein) Monoclonal Antibody(Clone: 169-1-E4.3)
Product Sizes
20 µg
£397.00
36-2757-20UG
100 µg
£716.00
36-2757-100UG
About this Product
- SKU:
- 36-2757
- Additional Names:
- AHUS2; Complement membrane cofactor protein; MCP; Measles virus receptor; Membrane cofactor protein; MIC10; TLX; Trophoblast leucocyte common antigen; Trophoblast lymphocyte cross reactive antigen
- translate.label.attr.clone:
- 169-1-E4.3
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a protein of 52kDa-58kDa; identified as CD46 (also known as membrane cofactor protein; MCP). Its epitope is located on the four immunogenic short consensus repeat (SCR) domains at N-terminus of the protein. CD46 exists as many isoforms in a variety of tissues. It is strongly expressed on salivary gland ducts and kidney ducts; moderately on lymphocytes and endothelium; and weakly on interstitial tissues and muscle cells; but not on erythrocytes. CD46 functions as a C3b/C4b-binding glycoprotein that inhibits complement activation on host cells. It also serves as a measles virus receptor; an adherence factor for group Streptococcus pyogenes; and a cellular pilus receptor for pathogenic Neisseria.
- Host:
- Mouse
- Immunogen:
- Stimulated human leukocytes
- Isotype:
- Mouse IgG2a; kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
