Anti-MCM6 (Proliferation Marker) Monoclonal Antibody(Clone: MCM6/3000)
Product Sizes
20 µg
£397.00
36-2748-20UG
100 µg
£716.00
36-2748-100UG
About this Product
- SKU:
- 36-2748
- Additional Names:
- DNA replication licensing factor MCM6; MCM6 minichromosome maintenance deficient 6; MIS5 homolog; p105MCM
- translate.label.attr.clone:
- MCM6/3000
- Clonality:
- Monoclonal
- Extra Details:
- The mini-chromosome maintenance (MCM) family of proteins; including MCM2; MCM3; MCM6 (Cdc21); MCM5 (Cdc46); MCM6 (Mis5) and MCM7 (Cdc47); are regulators of DNA replication that act to ensure replication occurs only once in the cell cycle. Expression of MCM proteins increases during cell growth; peaking at G1/S phase. The MCM proteins each contain an ATP-binding motif; which is predicted to mediate ATP-dependent opening of double-stranded DNA. MCM proteins are regulated by E2F transcription factors; which induce MCM expression; and by protein kinases; which interact with MCM proteins to maintain the post-replicative state of the cell. MCM2/MCM6 complexes function as substrates for Cdc2/cyclin B in vitro.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa 228-368) of human MCM6 protein (exact sequence is proprietary)
- Isotype:
- Mouse IgG2b; kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
