Anti-Cytokeratin 14 (KRT14) (Squamous Cell Marker) Monoclonal Antibody(Clone: KRT14/2375)
Product Sizes
20 µg
£397.00
36-2673-20UG
100 µg
£716.00
36-2673-100UG
About this Product
- SKU:
- 36-2673
- Additional Names:
- CK-14; Dowling Meara; ebs3; ebs4; Epidermolysis Bullosa Simplex; k14; Keratin 14; Keratin Type I Cytoskeletal 14; Koebner; krt14; NFJ
- translate.label.attr.clone:
- KRT14/2375
- Clonality:
- Monoclonal
- Extra Details:
- Cytokeratin 14 (CK14) belongs to the type I (or A or acidic) subfamily of low molecular weight keratins and exists in combination with keratin 5 (type II or B or basic). CK14 is found in basal cells of squamous epithelia; some glandular epithelia; myoepithelium; and mesothelial cells. Anti-CK14 is useful in differentiating squamous cell carcinomas from poorly differentiated epithelial tumors. Anti-CK14 is one of the specific basal markers for distinguishing between basal and non-basal subtypes of breast carcinomas. Anti-CK14 is also a good marker for differentiation of intraductal from invasive salivary duct carcinoma by the positive staining of basal cells surrounding the in-situ neoplasm as well as for differentiation of benign prostate from prostate carcinoma. Furthermore; this antibody has been useful in separating oncocytic tumors of the kidney from its renal mimics; and in identifying metaplastic carcinomas of the breast.
- Host:
- Mouse
- Immunogen:
- Recombinant human KRT14 fragment (around aa351-472) (exact sequence is proprietary)
- Isotype:
- Mouse IgG2a; kappa
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
