Anti-Cytokeratin 10 (Suprabasal Epithelial Marker) Monoclonal Antibody(Clone: AE20)
Product Sizes
20 µg
£397.00
36-2665-20UG
100 µg
£716.00
36-2665-100UG
About this Product
- SKU:
- 36-2665
- Additional Names:
- BCIE; BIE; EHK; Keratin Type I Cytoskeletal 10; KRT10
- translate.label.attr.clone:
- AE20
- Clonality:
- Monoclonal
- Extra Details:
- This MAb recognizes a protein of 56.5kDa; identified as cytokeratin 10 (CK10). CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis; expression of CK10 strictly parallels the extent of differentiation; it is absent in the basal layer; appears in the first suprabasal layers and increases in concentration towards the granular layer. However; CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm; clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm; clinical stages II and III); CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes; being preferentially detected in more-differentiated parts.
- Host:
- Mouse
- Immunogen:
- Human cytokeratin 10
- Isotype:
- Mouse IgG1; kappa
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
