Anti-CD61 / Integrin '3 / Platelet Glycoprotein IIIa (Platelet Marker) Monoclonal Antibody(Clone: rITGB3/2145)

Product Sizes

20 µg

£397.00

36-2622-20UG

100 µg

£716.00

36-2622-100UG

About this Product

SKU:: 36-2622
Additional Names:: BDPLT2; GP3A; GPIIIa; GT; HPA 1; HPA 4; Integrin beta-3; ITGB3; NAIT; Platelet fibrinogen receptor beta subunit; Platelet glycoprotein IIIa; PTP
translate.label.attr.clone:: rITGB3/2145
Clonality:: Monoclonal
Extra Details:: Reacts with human integrin beta3 (GPIIIa; vitronectin receptor beta chain). It associates with the V-chain (CD51) to form vitronectin receptor; or with the IIb-chain (CD41) to form the GpIIb/GpIIIa complex (CD41/CD61).The CD41/CD61 complex appears early in megakaryocyte maturation. The activated CD41/CD61 complex is a receptor for von Willebrand factor; soluble fibrinogen; fibronectin; vitronectin and thrombospondin. It plays a central role in platelet activation and aggregation. The CD51/CD61 is implicated in tumor metastasis and adenoviral infection. The antibody detects platelets in smears of blood and bone marrow; as well as megakaryocytes in frozen sections and cell smears. The antibody is useful for classification of megakaryoblastic leukemia.
Host:: Mouse
Immunogen:: Recombinant human ITGB3 protein fragment (aa 385-490) (exact sequence is proprietary)
Isotype:: Mouse IgG1; kappa
Reactivities:: Human
Shipping Conditions:: Blue Ice
Storage Conditions:: Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
Supplier:: Abeomics
Type:: Antibodies:Monoclonal Antibody

Basket