Anti-CD11c (Dendritic Cell Marker) Monoclonal Antibody(Clone: ITGAX/1243)
Product Sizes
20 µg
£397.00
36-2613-20UG
100 µg
£716.00
36-2613-100UG
About this Product
- SKU:
- 36-2613
- Additional Names:
- CD11 antigen-like family member C; Complement component 3 receptor 4 subunit; Integrin alpha-X; integrin; alpha X (antigen CD11C (p150); alpha polypeptide); Leu M5 alpha subunit; Leukocyte adhesion glycoprotein p150 95 alpha chain; Myeloid membrane antigen alpha subunit; p150/95
- translate.label.attr.clone:
- ITGAX/1243
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a protein of 145kDa; identified as CD11c. CD11c (ITGAX); a member of the leukointegrin family; shares the same beta subunit with other members of the leukocyte adhesion molecule family; which includes CD11a (LFA-1); CD11b (MAC-1) and CD11d (ITGAD); but has a unique alpha chain. CD11c has been shown to play a role in phagocytosis; cell migration; and cytokine production by monocytes/macrophages as well as induction of T-cell proliferation by Langerhans cells. CD11c is expressed prominently on the plasma membranes of monocytes; tissue macrophages; NK cells; and most dendritic cells (DCs). A lower level of expression is also observed on neutrophils as a result of its high level of expression on most DCs. An antibody to CD11c may aid in identification of lesions with histiocytic origin. It may also been used as a marker for hairy cell leukemia in paraffin-embedded tissues.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (aa 637-827) of human ITGAX protein (exact sequence is proprietary)
- Isotype:
- Mouse IgG2b; kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
