Anti-Interleukin 10 (IL10) (Immuno-regulation Marker) Monoclonal Antibody(Clone: IL10/2651R)
Product Sizes
20 µg
£397.00
36-2593-20UG
100 µg
£716.00
36-2593-100UG
About this Product
- SKU:
- 36-2593
- Additional Names:
- Cytokine Synthesis Inhibitory Factor (CSIF); GVHDS; IL-10; IL10; IL10A; Interleukin-10; T-cell Growth Inhibitory Factor (TGIF)
- translate.label.attr.clone:
- IL10/2651R
- Clonality:
- Monoclonal
- Extra Details:
- Interleukin 10 (IL10) is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immuno-regulation and inflammation. It down-regulates the expression of Th1 cytokines; MHC class II antigens; and costimulatory molecules on macrophages. It also enhances B cell survival; proliferation; and antibody production. This cytokine can block NF-kappa B activity; and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice sµggested the function of this cytokine as an essential immuno-regulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.
- Host:
- Rabbit
- Immunogen:
- Recombinant full-length human Interleukin 10 (IL10) protein
- Isotype:
- Rabbit IgG
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
