Anti-CD25 / IL2RA (Activated Lymphocyte Marker) Monoclonal Antibody(Clone: IL2RA/2394)
Product Sizes
20 µg
£397.00
36-2587-20UG
100 µg
£716.00
36-2587-100UG
About this Product
- SKU:
- 36-2587
- Additional Names:
- IL2 Receptor alpha; IL2R alpha chain; IL2R; IL2R subunit alpha IL2RA; Interleukin-2 receptor subunit alpha; Ly43; p55; p55 chain; T Cell Growth Factor Receptor; TAC antigen; TCGFR
- translate.label.attr.clone:
- IL2RA/2394
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a protein of 55kDa; identified as CD25. It is expressed on activated T- and B-cells and activated monocytes/macrophages. With respect to lymphomas; CD25 is present on malignant cells of Hodgkin's disease; HTLV-1+ adult T-cell leukemia; cutaneous T-cell lymphoma; and hair cell leukemia. Increased levels of soluble CD25 are observed in the leukemias/lymphomas and inflammatory/ autoimmune diseases. CD25 molecule alone appears to function as a low affinity receptor and associates with CD122 (IL-2R chain; p75) and CD132 (common chain) to form the high affinity IL-2 receptor complex. CD25 antibodies detect three epitope regions; A; B and C. This MAb recognizes the epitope B; which is located at residue 3-104 of CD25 and doe not block IL-2 binding to CD25.
- Host:
- Mouse
- Immunogen:
- Recombinant human IL2RA protein fragment (around aa 42-183) (exact sequence is proprietary)
- Isotype:
- Mouse IgG2b; kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
