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Antibodies

Anti-Kappa Light Chain / IGKC (B-Cell Marker) Monoclonal Antibody(Clone: KLC709)-CF488

Product Sizes
0.5 at 100 ml at µg/ml
£716.00
36-2567-0.5AT100MLATUG
About this Product
SKU:
36-2567
Additional Names:
HCAK1; Ig Kappa Chain C Region; IGKC; Immunoglobulin KM
translate.label.attr.clone:
KLC709
Clonality:
Monoclonal
Conjugate:
CF488
Extra Details:
This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. It recognizes human Ig kappa light chains of both secreted and cell surface immunoglobulin. It detects also free kappa light chains. In mammals; the two light chains in an antibody are always identical; with only one type of light chain; kappa or lambda. The ratio of Kappa to Lambda is 70:30. However; with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias; plasmacytomas; and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
Host:
Mouse
Immunogen:
Recombinant full-length human IGKC protein
Isotype:
Mouse IgG1; kappa
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 4 to 8[o]C. Antibody is stable for 24 months. Non-hazardous.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
  • Manufacturer's Data Sheet:1.jpg