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Antibodies

Anti-Heat Shock 27kDa Protein 1 Monoclonal Antibody(Clone: CPTC-HSPB1-2)

Product Sizes
20 µg
£397.00
36-2505-20UG
100 µg
£716.00
36-2505-100UG
About this Product
SKU:
36-2505
Additional Names:
Heat shock 27kDa protein; Estrogen-regulated 24kDa protein; Heat shock 25kDa protein 1; Heat shock 28kDa protein 1; Heat shock protein beta-1; HMN2B; Hsp25; Hsp28; HspB1; Stress-responsive protein 27 (SRP27)
translate.label.attr.clone:
CPTC-HSPB1-2
Clonality:
Monoclonal
Extra Details:
HSP27; also referred to as the Estrogen-Regulated 24K protein and HSP28; is one of several small heat shock proteins produced by all organisms studied. HSP27 synthesis is induced by elevated temperature; as well as by estrogen in hormone responsive cells. Interestingly; human HSP27 also shares greater than 50% homology with low molecular weight Drosophila HSPs and mammalian -crystalline lens protein. Because of the estrogen responsive nature of HSP27; this protein has been studied extensively in human estrogen responsive tissues such as cervix; endometrium and breast tissue. Therefore; HSP27 may be useful in classifying various hormone sensitive tumors.
Host:
Mouse
Immunogen:
Recombinant human full-length protein
Isotype:
Mouse IgG1; kappa
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
  • Manufacturer's Data Sheet:1.jpg
Fig. 2: Formalin-fixed; paraffin-embedded human Prostate stained with HSP27 Mouse Monoclonal Antibody (CPTC-HSPB1-2).
Fig. 3: Immunofluorescence Analysis of PFA-fixed MCF-7 cells labeling HSP27 with HSP27 Mouse Monoclonal Antibody (CPTC-HSPB1-2) followed by Goat anti-Mouse IgG-CF488 (Green). The nuclear counterstain is Reddot (Red)
Fig. 4: Flow Cytometric Analysis of PFA-fixed MCF-7 cells using HSP27 Mouse Monoclonal Antibody (CPTC-HSPB1-2) followed by Goat anti- Mouse- IgG-CF488 (Blue); Isotype Control (Red).
Fig. 4: Flow Cytometric Analysis of PFA-fixed MCF-7 cells using HSP27 Mouse Monoclonal Antibody (CPTC-HSPB1-2) followed by Goat anti- Mouse- IgG-CF488 (Blue); Isotype Control (Red).
Fig. 5: Analysis of Protein Array containing more than 19;000 full-length human proteins using HSP27 Mouse Monoclonal Antibody (CPTC-HSPB1-2). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that a