Anti-Serum Amyloid P / APCS Monoclonal Antibody(Clone: APCS/3240)
Product Sizes
20 µg
£397.00
36-2503-20UG
100 µg
£716.00
36-2503-100UG
About this Product
- SKU:
- 36-2503
- Additional Names:
- 9.5S alpha 1 glycoprotein; Amyloid P component serum (APCS); Pentaxin related; Pentraxin 2 (PTX2); Serum Amyloid P (SAP); Serum amyloid P component
- translate.label.attr.clone:
- APCS/3240
- Clonality:
- Monoclonal
- Extra Details:
- Serum amyloid P (SAP) is a glycoprotein belonging to the pentraxin family of proteins; which has a characteristic pentameric organization and calciumdependent ligand binding. Secreted by liver epithelial cells; SAP is found in serum and urine. Althoµgh the function of SAP has not been clearly established; it has been shown to interact with DNA and histones and is thoµght to play a role in scavenging nuclear material released from damaged circulating cells. Also designated PTX2; SAP is a precursor of the protein amyloid P component (AP); which is universally associated with the amyloid deposits in all forms of amyloidoses; including Alzheimer s disease. SAP is a decamer of ten identical; noncovalently linked subunits; each of which may be post-translationally modified by glycosylation.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment of human APCS protein (around aa 143-223) (exact sequence is proprietary)
- Isotype:
- Mouse IgG2b; kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
