Anti-HLA-DR (MHC II) Monoclonal Antibody(Clone: SPM289)
Product Sizes
20 µg
£397.00
36-2487-20UG
100 µg
£716.00
36-2487-100UG
About this Product
- SKU:
- 36-2487
- Additional Names:
- DR alpha chain; DRB1; DRB4; HLA class II histocompatibility antigen; HLA class II histocompatibility antigen DR alpha chain; HLA DR1B; HLA DR3B; HLA DRA; HLA DRA1; HLA DRB1; HLA DRB3; HLA DRB4; HLA DRB5; HLA-DRA; HLADR4B; HLADRA1; HLADRB; Major histocompatibility complex class II DR alpha; Major his
- translate.label.attr.clone:
- SPM289
- Clonality:
- Monoclonal
- Extra Details:
- This MAb reacts with the beta-chain of HLA-DR antigen; a member of MHC class II molecules. It does not cross react with HLA-DP and HLA-DQ. The L243 antibody recognizes a different epitope than the SPM289 monoclonal antibody; and these antibodies do not cross-block binding to each other's respective epitopes. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kDa alpha (heavy) chain and a 28kDa beta (light) chain. It is expressed on B-cells; activated T-cells; monocytes/macrophages; dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules; HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts.
- Host:
- Mouse
- Immunogen:
- Activated human peripheral blood mononuclear cells
- Isotype:
- Mouse IgG2b; kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
