Anti-HLA-DRA (MHC II) Monoclonal Antibody(Clone: IPO-10)
Product Sizes
20 µg
£397.00
36-2486-20UG
100 µg
£716.00
36-2486-100UG
About this Product
- SKU:
- 36-2486
- Additional Names:
- DR alpha chain; HLA class II histocompatibility antigen; HLA class II histocompatibility antigen DR alpha chain; HLA DRA; HLA DRA1; HLA-DRA; HLADRA1; Major histocompatibility complex class II DR alpha; MHC cell surface glycoprotein; MHC class II antigen DRA
- translate.label.attr.clone:
- IPO-10
- Clonality:
- Monoclonal
- Extra Details:
- MAb IPO-10 defines the antigen; which appears on B cell progenitors following HLA-DR and preceding CD10; CD19; CD22; CD37 and cym. It is expressed on resting B cells and than reappears and persists in cytoplasm and on cell surface until cytoplasmic Ig appears. It is a useful antibody for diagnostics of neoplasms of B cell origins. It reacts with human B cell lines Daudi; Raji; Namalva; EB-3; RPMI-8226 (50% of cells). The MAb does not label T cell lines; blood granulocytes; thymocytes or bone marrow stromal fibroblasts. No significant changes are detected after PHA or ConA stimulation while LPS and PWM stimulated cultures after 18-48h show decreased number of antigen-positive cells but in final terms of cultivation antigen is expressed again. This MAb labels B cell leukemias and some lymphomas. Hairy cell leukemia strongly reacts and 70% of B cell CLL and some B-NHL were also positive. IPO-10 reacts with AMML cells and in a majority of Hodgkin's disease cases a significant percentage of affected lymph node cells were detected. '
- Host:
- Mouse
- Immunogen:
- Spleen cells of a patient with hairy cell leukemia (Daudi cells)
- Isotype:
- Mouse IgG3; kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
