Anti-HLA-DP/-DQ/-DR (MHC II) Monoclonal Antibody(Clone: CR3/43)
Product Sizes
20 µg
£397.00
36-2480-20UG
100 µg
£716.00
36-2480-100UG
About this Product
- SKU:
- 36-2480
- Additional Names:
- HLA-DPB1; HLA-DQA1; HLA-DQB1; HLA-DRA; HLA-DRB1; HLA-DRB3; HLA-DRB4; HLA-DRB5;
- translate.label.attr.clone:
- CR3/43
- Clonality:
- Monoclonal
- Extra Details:
- Reacts with a common epitope of human major histocompatibility (MHC) class II antigens; HLA-DP; -DQ and -DR. Human MHC class II antigens are transmembrane glycoproteins composed of an chain (36kDa) and a chain (27kDa). They are expressed primarily on antigen presenting cells such as B lymphocytes; monocytes; macrophages; and thymic epithelial cells and are also present on activated T lymphocytes. Human MHC class II genes are located in the HLA-D region that encodes at least six and ten chain genes. Three loci; DR; DQ and DP; encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They; therefore; have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles.
- Host:
- Mouse
- Immunogen:
- Cells from human tonsil
- Isotype:
- Mouse IgG1; kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
