Anti-HLA-A (MHC I) Monoclonal Antibody(Clone: 108-2C5)
Product Sizes
20 µg
£397.00
36-2474-20UG
100 µg
£716.00
36-2474-100UG
About this Product
- SKU:
- 36-2474
- Additional Names:
- HLA-A; HLA class 1A; MHC class I HLA-A
- translate.label.attr.clone:
- 108-2C5
- Clonality:
- Monoclonal
- Extra Details:
- HLA-A; with HLA-B and HLA-C; belongs to major histocompatibility complex (MHC) class I antigens and expresses constitutively on all nucleated cells. MHC class I antigens play a role in class I MHC-associated antigen presentation; inhibition of NK cell cytotoxicity; tumor surveillance; and tissue allotransplantation. This MAb is useful for HLA molecular typing of peripheral blood leukocytes as well as a large number of leukemic cell lines. It reacts with an intralocus determinant present on a limited number of HLA-A locus-encoded gene products (HLA-A2; -A3; -A28; -A29; -A30; -A31 and -Aw33). Its epitope maps between aa65-to-aa80 of the 1 domain of the HLA-A. This MAb recognizes an intralocus determinant present on a limited number of HLA-A locus-encoded gene products (HLA-A2; -A3; A28; -A29; -A30; -A31 and -Aw33). Furthermore; by testing its reactivity with HLA-A2 natural variants and mutants; the importance of amino acid residues 79 and/or 80 of the alpha1 domain was demonstrated in the formation of an intralocus HLA-A determinant.
- Host:
- Mouse
- Immunogen:
- Normal human peripheral blood lymphocytes
- Isotype:
- Mouse IgG1; kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
