Anti-CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) Monoclonal Antibody(Clone: C209/2749R)
Product Sizes
20 µg
£397.00
36-2467-20UG
100 µg
£716.00
36-2467-100UG
About this Product
- SKU:
- 36-2467
- Additional Names:
- CD209; CDSIGN; CIRE; CLEC4L; DC-SIGN; DC-SIGN1; DCSIGN; Dendritic cell-specific ICAM-3 Grabbing Non-integrin 1; HIV GP120 Binding Protein; SIGN-R1; SIGNR5
- translate.label.attr.clone:
- C209/2749R
- Clonality:
- Monoclonal
- Extra Details:
- DC-SIGN is a transmembrane receptor that is expressed on the surface of dendritic cells and macrophages. It is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses. The protein is organized into three distinct domains: an N-terminal transmembrane domain; a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization; which allows the receptor to bind multivalent ligands with high avidity.
- Host:
- Rabbit
- Immunogen:
- Recombinant full-length human CD209 protein
- Isotype:
- Rabbit IgG
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
