Anti-Granzyme B (NK/T-Cell Lymphoma Marker) Monoclonal Antibody(Clone: GZMB/2403)
Product Sizes
20 µg
£397.00
36-2449-20UG
100 µg
£716.00
36-2449-100UG
About this Product
- SKU:
- 36-2449
- Additional Names:
- Cathepsin G-like 1; CCPI; CGL1; CSPB; CTLA-1; CTSGL1; Cytotoxic serine protease B; Cytotoxic T lymphocyte associated serine esterase 1; Cytotoxic T-lymphocyte proteinase 2; Fragmentin-2; Human lymphocyte protein (Hlp); Lymphocyte protease; SECT; T-cell serine protease 1-3E
- translate.label.attr.clone:
- GZMB/2403
- Clonality:
- Monoclonal
- Extra Details:
- Granzyme B is a member of the granule serine protease family stored specifically in NK cells or cytotoxic T cells. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the ability to recognize; bind; and lyse specific target cells. They are thoµght to protect their host by lysing cells bearing on their surface 'nonself' antigens; usually peptides or proteins resulting from infection by intracellular pathogens. Granzyme B is crucial for the rapid induction of target cell apoptosis by CTLs in the cell-mediated immune response. Granzyme B is useful as a marker in the identification of NK/T-cell lymphomas. High percentages of cytotoxic T-cells have been shown to be an unfavorable prognostic indicator in Hodgkin's Disease.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment of human GZMB protein (around aa 73-187) (exact sequence is proprietary)
- Isotype:
- Mouse IgG2b; lambda
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
