Anti-GP2 (Glycoprotein 2) / ZAP75 Monoclonal Antibody(Clone: GP2/3416)
Product Sizes
20 µg
£397.00
36-2412-20UG
100 µg
£716.00
36-2412-100UG
About this Product
- SKU:
- 36-2412
- Additional Names:
- Glycoprotein 2 (zymogen granule membrane); GP2; Pancreatic zymogen granule membrane associated protein GP2; Pancreatic zymogen granule membrane protein GP-2; ZAP75
- translate.label.attr.clone:
- GP2/3416
- Clonality:
- Monoclonal
- Extra Details:
- GP2 (glycoprotein 2); also known as ZAP75; is a 537 amino acid secreted protein. It is an integral membrane protein that is secreted from intracellular zymogen granules and associates with the plasma membrane via glycosylphosphatidylinositol (GPI) linkage. GP2 is cleaved and then released into the pancreatic duct along with exocrine secretions. GP2 binds pathogens such as enterobacteria; thereby playing an important role in the innate immune response. The C-terminus of this protein is related to the C-terminus of the protein encoded by the neighboring gene; uromodulin (UMOD). GP2 is also expressed on the apical plasma membrane of specialized microfold (M) cells among enterocytes and serves as a transcytotic receptor for mucosal antigens. M cells are considered a promising target for oral vaccination against various infectious diseases.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment of human GP2 protein (around aa 35-179) (exact sequence is proprietary)
- Isotype:
- Mouse IgG2c; kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
