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Antibodies

Anti-14-3-3 Sigma / Stratifin Monoclonal Antibody(Clone: CPTC-SFN-2)

Product Sizes
20 µg
£397.00
36-2407-20UG
100 µg
£716.00
36-2407-100UG
About this Product
SKU:
36-2407
Additional Names:
SFN; HME1; Stratifin; YWHAS; 14-3-3 Sigma
translate.label.attr.clone:
CPTC-SFN-2
Clonality:
Monoclonal
Extra Details:
SFN (stratifin) is a p53-induced tumor suppressor gene which is activated in response to DNA damage; causing cell cycle arrest at G2 phase by blocking cdc2-cyclin B1 complex from entering the nucleus. It is inactivated in breast; lung; prostate; liver and gastric cancer. It is associated with poor prognosis when its down-regulation is observed in epithelial ovarian cancer. SFN expression could contribute to cancer cell proliferation and the development and/or progression of human gastrointestinal cancer.
Host:
Mouse
Immunogen:
Recombinant human full-length SFN protein
Isotype:
Mouse IgG1; kappa
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
  • Manufacturer's Data Sheet:1.jpg
Fig. 2: SDS-PAGE Analysis Purified Stratifin Mouse Monoclonal Antibody (CPTC-SFN-2). Confirmation of Integrity and Purity of Antibody.
Fig. 3: Western Blot Analysis of Human PC-3 cell lysate using Stratifin Mouse Monoclonal Antibody (CPTC-SFN-2).
Fig. 4: Analysis of Protein Array containing more than 19;000 full-length human proteins using 14-3-3 Sigma / Stratifin Mouse Monoclonal Antibody (CPTC-SFN-2). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals ge
Fig. 4: Analysis of Protein Array containing more than 19;000 full-length human proteins using 14-3-3 Sigma / Stratifin Mouse Monoclonal Antibody (CPTC-SFN-2). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals ge