Anti-NKX2.8 Monoclonal Antibody(Clone: NKX28/2547)
Product Sizes
20 µg
£397.00
36-2376-20UG
100 µg
£716.00
36-2376-100UG
About this Product
- SKU:
- 36-2376
- Additional Names:
- Homeobox protein NK 2 homolog H; Homeobox protein NK-2 homolog H; Homeobox protein Nkx 2.8; Homeobox protein Nkx-2.8; NK 2 homolog 8; NK 2 homolog H; NK2 homeobox 8; NK2 transcription factor related; locus 8; Nkx2 9; Nkx2-8; NKX2.8; NKX28_HUMAN; NKX2G; NKX2H; OTTHUMP00000027959
- translate.label.attr.clone:
- NKX28/2547
- Clonality:
- Monoclonal
- Extra Details:
- The protein encoded by this gene is a homeobox-containing developmental regulator associated with liver development. The encoded protein binds to the alpha-fetoprotein (AFP) gene promoter and increases the expression of AFP. This gene is overexpressed in some lung cancers and is linked to poor patient survival; possibly due to its resistance to cisplatin. This gene is aberrantly methylated in pancreatic cancer; deleted in squamous cell lung carcinomas; and acts as a tumor suppressor in esophageal cancer. Mutations in this gene may also be a cause of neural tube defects.
- Host:
- Mouse
- Immunogen:
- Human recombinant NKX2.8 protein fragment (around aa 10-123) (exact sequence is proprietary)
- Isotype:
- Mouse IgG1; kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
