Anti-PAI-RBP1 / SERBP1 / SERPINE1 Monoclonal Antibody(Clone: SERBP1/3497)
Product Sizes
20 µg
£397.00
36-2368-20UG
100 µg
£716.00
36-2368-100UG
About this Product
- SKU:
- 36-2368
- Additional Names:
- CGI 55; CHD3IP; Chromodomain helicase DNA binding protein 3 interacting protein; HABP4L; PAI1 RNA-binding protein 1; PAIRBP1; Plasminogen activator inhibitor 1 RNA binding protein; SERPINE1 mRNA binding protein 1
- translate.label.attr.clone:
- SERBP1/3497
- Clonality:
- Monoclonal
- Extra Details:
- PAI-RBP1 (plasminogen activator inhibitor 1 RNA-binding protein); also known as SERBP1 (SERPINE1 mRNA-binding protein 1); CGI-55; CHD3IP (chromodomain helicase DNA binding protein 3 interacting protein); HABP4L or PAI-RBP1; is a membrane-associated protein that localizes to the nucleus; the perinuclear region of the cytoplasm and the plasma membrane. PAI-RBP1 is believed to play a role in the regulation of mRNA stability; as it specifically binds to the CRS (cyclic nucleotide-responsive sequence) motif of the PAI-1 mRNA and acts to stabilize the mRNA and regulate its expression. In addition; PAI-RBP1 interacts with Mi2- and may be involved in chromatin remodeling. PAI-RBP1 also interacts with PGRMC1 and participates in the transduction of Progesterone s antiapoptotic action in ovarian cell types. The gene encoding PAI-RBP1 is overexpressed in ovarian cancer; sµggesting a possible role for PAI-RBP1 in tumorigenesis and tumor metastasis.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment of human SERBP1 protein (around aa3-139) (exact sequence is proprietary)
- Isotype:
- Mouse IgG2c; kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
