Anti-Ku (p70/p80) (Nuclear Marker) Monoclonal Antibody(Clone: KU729)-CF488
Product Sizes
0.5 at 100 ml at µg/ml
£716.00
36-2358-0.5AT100MLATUG
About this Product
- SKU:
- 36-2358
- Additional Names:
- Ku (p70): 70kDa subunit of Ku antigen; ATP dependent DNA helicase 2 subunit 1; ATP-dependent DNA helicase II 70kDa subunit; CTC box-binding factor 75kDa subunit; CTC75; CTCBF; DNA repair protein XRCC6; G22P1; Ku autoantigen; 70kDa; Ku70; Kup70; Lupus Ku autoantigen protein p70; ML8; Thyroid autoanti
- translate.label.attr.clone:
- KU729
- Clonality:
- Monoclonal
- Conjugate:
- CF488
- Extra Details:
- Recognizes a dimer of two proteins of 70kDa and ~80kDa; identified as two subunits of Ku. MAb KU729 recognizes a conformational epitope of p70/p80 dimer; which is destroyed during Western blotting. The p70/p80 dimer is important for function of a 460kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling; proliferation; DNA repair; replication; transcriptional activation; and apoptosis.
- Host:
- Mouse
- Immunogen:
- Nuclear extract of human HL-60 cells
- Isotype:
- Mouse IgG1; kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 4 to 8[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
