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Antibodies

Anti-Alkaline Phosphatase (Placental) / PLAP (Germ Cell Tumor Marker) Monoclonal Antibody(Clone: ALPP/516)

Product Sizes
20 µg
£397.00
36-2339-20UG
100 µg
£716.00
36-2339-100UG
About this Product
SKU:
36-2339
Additional Names:
Alkaline phosphatase placental type; Alkaline phosphatase Regan Isozyme; ALP; Alp1; ALPP; Germ-cell alkaline phosphatase; nagao Isozyme; PALP; Placental alkaline phosphatase 1; placental heat-stable alkaline phosphatase; PLAP-1; PLAP1
translate.label.attr.clone:
ALPP/516
Clonality:
Monoclonal
Extra Details:
PLAP is a tissue specific; trophoblast-derived; 70kDa; glycosyl-phosphatidylinositol (GPI)-anchored; dimeric; Zn2+ metallo-glycoprotein that catalyzes the hydrolysis of phosphomonoesters into an inorganic phosphate and an alcohol. It is present in the placenta and serum of pregnant women and in high frequency in gynecological and testicular cancers and in lower frequency in other tumors. The three tissue-specific AP's in humans; PLAP; germ cell AP (GCAP) and intestinal AP; are 90-98% homologous. Non-tissue specific AP is found in kidney; liver and bone. This MAb binds equally well to all common allelic variants (S; F; FS and I) of PLAP and to some variants of AP from normal human testis. This MAb can be used as tracer antibody in ELISA to detect PLAP in serum of S; F; FS and I phenotypes.
Host:
Mouse
Immunogen:
Recombinant full-length human ALPP protein
Isotype:
Mouse IgG1; kappa
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
  • Manufacturer's Data Sheet:1.jpg