Anti-Alkaline Phosphatase (Tissue-Nonspecific) Monoclonal Antibody(Clone: SPM372)
Product Sizes
20 µg
£397.00
36-2335-20UG
100 µg
£716.00
36-2335-100UG
About this Product
- SKU:
- 36-2335
- Additional Names:
- Alkaline phosphatase; germ cell; Alkaline phosphatase; testicular and thymus; Alkaline phosphatase liver/bone/kidney; Alkaline phosphatase; tissue-nonspecific; ALPG; ALPL; Germ cell alkaline phosphatase; Testicular and thymus alkaline phosphatase; Tissue non-specific alkaline phosphatase; Tissue non
- translate.label.attr.clone:
- SPM372
- Clonality:
- Monoclonal
- Extra Details:
- There are at least four distinct but related alkaline phosphatases: intestinal; placental; placental-like; and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2; while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is; therefore; referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization; however; mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypo-phosphatasia; a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary; however; depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively spliced transcript variants; which encode the same protein; have been identified for this gene.
- Host:
- Mouse
- Immunogen:
- Bovine intestinal alkaline phosphatase
- Isotype:
- Mouse IgG1; kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
