Anti-CELA3B / ELA3B (Pancreatic Function Marker) Monoclonal Antibody(Clone: CELA3B/1257)
Product Sizes
20 µg
£397.00
36-2309-20UG
100 µg
£716.00
36-2309-100UG
About this Product
- SKU:
- 36-2309
- Additional Names:
- Chymotrypsin like elastase family member 3B (CELA3B); ELA3B; Elastase IIIB; Protease E
- translate.label.attr.clone:
- CELA3B/1257
- Clonality:
- Monoclonal
- Extra Details:
- This MAb recognizes a protein of ~30kDa; identified as CELA3B (Chymotrypsin like elastase family member 3B). Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1; 2; 2A; 2B; 3A; and 3B. Unlike other elastases; elastase 3B has little elastolytic activity. Like most of the human elastases; elastase 3B is secreted from the pancreas as a zymogen and; like other serine proteases such as trypsin; chymotrypsin and kallikrein; it has a digestive function in the intestine. Elastase 3B preferentially cleaves proteins after alanine residues. Elastase 3B may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1; and excretion of this protein in fecal material is frequently used as a measure of pancreatic function in clinical assays.
- Host:
- Mouse
- Immunogen:
- Recombinant human CELA3B protein fragment (around aa 82-238) (exact sequence is proprietary)
- Isotype:
- Mouse IgG1; kappa
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
