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Antibodies

Anti-Aldo-keto Reductase Family 1 Member B1 (Adrenal Marker) Monoclonal Antibody(Clone: CPTC-AKR1B1-3)

Product Sizes
20 µg
£397.00
36-2288-20UG
100 µg
£716.00
36-2288-100UG
About this Product
SKU:
36-2288
Additional Names:
AKR1B1; Aldehyde reductase; aldehyde reductase 1; Aldo-keto reductase family 1 member B1; aldo-keto reductase family 1; member B1 (aldose reductase); Aldose reductase; AR; Lii5-2 CTCL tumor antigen; low Km aldose reductase
translate.label.attr.clone:
CPTC-AKR1B1-3
Clonality:
Monoclonal
Extra Details:
AKR1B1; also designated as aldose reductase; is a member of the aldo/keto reductase superfamily; which consists of more than 40 known enzymes and proteins. This protein catalyzes the reduction of a number of aldehydes; including the aldehyde form of glucose; and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. It has also been shown to have decreased expression in adrenocortical cancer; and possibly play a role in adrenal tumorigenesis. It has been sµggested that AKR1B1 could be investigated as a marker of malignancy for adrenal tumor diagnosis.
Host:
Mouse
Immunogen:
Recombinant human full-length AKR1B1 protein
Isotype:
Mouse IgG1; kappa
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
  • Manufacturer's Data Sheet:1.jpg
Fig. 2: SDS-PAGE Analysis Purified AKR1B1 Mouse Monoclonal Antibody (CPTC-AKR1B1-3). Confirmation of Purity and Integrity of Antibody.
Fig. 3: Western Blot Analysis of Human Kidney tissue; Human HepG2; HEK293; HeLa and Jurkat cell lysate using AKR1B1 Mouse Monoclonal Antibody (CPTC-AKR1B1-3).
Fig. 4: Immunofluorescence Analysis of A549 cells labeling AKR1B1 with AKR1B1 Mouse Monoclonal Antibody (CPTC-AKR1B1-3) followed by Goat anti-Mouse IgG-CF488 (Green). The nuclear counterstain is Redot (Red)
Fig. 4: Immunofluorescence Analysis of A549 cells labeling AKR1B1 with AKR1B1 Mouse Monoclonal Antibody (CPTC-AKR1B1-3) followed by Goat anti-Mouse IgG-CF488 (Green). The nuclear counterstain is Redot (Red)
Fig. 5: Analysis of Protein Array containing more than 19;000 full-length human proteins using Aldo-keto Reductase Family 1 Member B1 Mouse Monoclonal Antibody (CPTC-AKR1B1-3). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value