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Antibodies

Anti-EGFR (Epidermal Growth Factor Receptor) Monoclonal Antibody(Clone: GFR450)-CF488

Product Sizes
0.5 at 100 ml at µg/ml
£716.00
36-2194-0.5AT100MLATUG
About this Product
SKU:
36-2194
Additional Names:
Erbb1; ERBB1; Errp; HER1; mENA; PIG61; Proto-oncogene c-ErbB-1; Receptor Tyrosine Protein Kinase; ErbB1; Urogastrone; wa2; Wa5
translate.label.attr.clone:
GFR450
Clonality:
Monoclonal
Conjugate:
CF488
Extra Details:
This MAb recognizes a protein of 170kDa; identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1; -2; -3 -4 or HER-1; -2; -3 -4. It binds to Epidermal Growth Factor (EGF); Transforming Growth Factor-a (TGF-alphaa); Heparin-binding EGF (HB-EGF); amphiregulin; betacellulin and epiregulin. EGFR is overexpressed in tumors of breast; brain; bladder; lung; gastric; head neck; esophagus; cervix; vulva; ovary; and endometrium. It is predominantly present in squamous cell carcinomas.
Host:
Mouse
Immunogen:
Recombinant extracellular domain of human EGFR protein
Isotype:
Mouse IgG2a; kappa
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 4 to 8[o]C. Antibody is stable for 24 months. Non-hazardous.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
  • Manufacturer's Data Sheet:1.jpg
Fig. 2: Flow Cytometry of EGFR on Mouse NIH/3T3 cells. Black: cells alone; Grey: Isotype Control; Green: CF488-labeled EGFR Monoclonal Antibody (GFR450).
Fig. 3: Confocal Immunofluorescent analysis of A431 cells using CF488-labeled EGFR Monoclonal Antibody (GFR450) (Green). DAPI was used to stain the cell nuclei (blue).
Fig. 4: Confocal Immunofluorescent analysis of A431 cells using CF488-labeled Isotype Control MAb (IgG2a) (Green). DAPI was used to stain the cell nuclei (blue). (Negative Control)
Fig. 4: Confocal Immunofluorescent analysis of A431 cells using CF488-labeled Isotype Control MAb (IgG2a) (Green). DAPI was used to stain the cell nuclei (blue). (Negative Control)