Anti-Desmoglein-1 (DSG1) Monoclonal Antibody(Clone: DSG1/1733)
Product Sizes
20 µg
£397.00
36-2175-20UG
100 µg
£716.00
36-2175-100UG
About this Product
- SKU:
- 36-2175
- Additional Names:
- Cadherin family member 4; CDHF4; Desmoglein-1; Desmosomal glycoprotein 1; DG1; DSG1; EPKHE; EPKHIA; Pemphigus foliaceus antigen; PPKS1; SPPK1
- translate.label.attr.clone:
- DSG1/1733
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a protein of ~150kDa; identified as Desmoglein-1 (DSG1). Desmoglein-1 is a member of the desmosomal cadherin family.Desmosomes are intercellular adhering junctions that represent cell surface attachment sites for intermediate filament. Desmocollins and desmogleins are the main desmosomal transmembrane proteins. Desmogleins consist of Dsg1; Dsg2; Dsg3; and Dsg4 isoforms.Within the desmosome; the extracellular domain of desmoglein is essential for calcium dependent heterophilic binding to the desmocollins; whereas the intracellular domain is essential for binding to the desmosomal plaque protein; plakoglobin. Desmoglein 1 is synthesized exclusively in the suprabasal layers. Intact and functionally active desmoglein 1 is essential to epidermal integrity.
- Host:
- Mouse
- Immunogen:
- Recombinant human desmoglein-1 protein fragment corresponding to intracellular domain
- Isotype:
- Mouse IgG1; kappa
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8[o]C. Antibody without azide - store at -20 to -80[o]C. Antibody is stable for 24 months. Non-hazardous.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
